There are many updates of COVID-19 has come out which are may be good or may be bad. These updates are about COVID-19 vaccine and according to scientists, this vaccine is ore effective then they had expect which is in under-development and the rate with which scientists are working on this, it is expected that it will launch soon but it creates too many questions on it like when we will get this vaccine?, what will be the side effect? and how much effective is this?
When any vaccine is created then three phase trails are done on it as in 1st phase vaccine is tested on 20- 80 people, in 2nd phase vaccine is tested on 100-300 people and in phase 3rd vaccine is tested on more than 1000 people. During July 2020 there were many companies which were trying to start phase 3 trails of the vaccine created by them and there was a company Moderna which starts phase 3 trails on 27 July 2020 in which there were 30,000 participants and on 16 November 2020 Moderna announced preliminary analysis in which it was found that the COVID-19 vaccine is 94.5% effective. In the 3rd phase 30,000 participants was divided into two parts as 1500 and 1500 roughly, to one part vaccine was given to the people and the other part get Placebo instead of vaccine which is a fake vaccine and it was found that from the 30,000 participants only 95 people get corona and from these 95, 90 participants got Placebo and 5 got vaccine, from all this its effectiveness can be estimated.
Second vaccine which is in the list is Pfizer vaccine which is mainly creating in Germany and for this phase 3 trail is done of 43000 people and found that this vaccine is 95% effective and the good thing for this is, its effectiveness not much decrease for old people. In both the Moderna and Pfizer vaccine there is a problem as these vaccine can only be stored in deep freeze, specifically at -70 degree Celsius which creates a big problem in transportation.
Now every vaccine has side effect and these vaccines also have. The safety of taking vaccine can judge by its danger of side effects but the good news in both the vaccine didn't have much dangerous side effect but there are number of mild side effects. In the trail of Moderna it was found that 9.7% participants got fatigue, 8.9% got muscle pain, 5.2% got joint pain and 4.5% got headache. For Pfizer vaccine percentage reduces for the same things like 3.8% got fatigue and 2% got headache. But still these vaccines are doubtful for long term side effect because all the observations are done in very short time and for this FDA has said that company should have to show two months safety data before the implementation of the vaccine which is also a short time but there is also need to implement it as soon as possible.
There is also a question that who will get vaccine first? Most of the people thought that the frontline workers has to be vaccinated first which is right thing because firstly we should have to stop this disease to spread all over. There are many countries which has done advance purchase commitment of vaccine as which the company got approval then firstly company have to sell vaccine to these countries but such countries are still in much risk because it is not sure that whether this vaccine will work properly or not in the real field.
Recently there are almost 13 vaccines which are in phase 3 trail and there are 6 vaccines which got early approval and are in limited use. It is not in known that when these vaccines will implement but governments are targeting 400-500 doses of COVID-19 vaccine by July 2021.
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